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Steroid Conversion Calculator
Steroid Conversion Calculator
Converts equivalent doses of corticosteroids for therapy adjustments

Steroid Conversion Calculator
Steroid Conversion Calculator
Converts equivalent doses of corticosteroids for therapy adjustments
Instructions
The steroid conversion calculator helps determine equivalent doses when switching between different corticosteroids. Users enter the current drug, dose and the target steroid for conversion. The tool applies standard equivalence factors to give the adjusted dose.
Overview
When to use
Why use
Evidences
Interpretation
Steroid | Dosage | Action duration |
Hydrocortisone | 20 mg | Short acting |
Prednisone/Prednisolone | 5 mg | Intermediate |
Methylprednisolone | 4 mg | Intermediate |
Dexamethasone | 0.75 mg | Long acting |
Betamethasone | 0.6 mg | Long acting |
Equivalency framework (StatPearls – Glucocorticoid therapy): Common oral/parenteral anti-inflammatory equivalences center on prednisone 5mg ≈ prednisolone 5mg ≈ methylprednisolone 4mg ≈ triamcinolone 4mg ≈ hydrocortisone 20mg ≈ dexamethasone 0.75mg ≈ betamethasone 0.6mg; mineralocorticoid activity varies substantially (hydrocortisone and fludrocortisone highest; dexamethasone/betamethasone negligible).
https://www.ncbi.nlm.nih.gov/books/NBK596734/
Study focus and design: Classic comparative human study evaluating the relative potency and duration of action of systemic glucocorticoids namely hydrocortisone, prednisone and dexamethasone, by measuring suppression and recovery of the hypothalamic–pituitary–adrenal (HPA) axis after dosing
https://pubmed.ncbi.nlm.nih.gov/888843/
Overview
When to use
Why use
Evidences
Corticosteroids are widely used in medicine for their anti-inflammatory and immunosuppressive effects. They are prescribed for conditions such as asthma, chronic obstructive pulmonary disease (COPD), autoimmune disorders, allergic reactions, and after organ transplantation. Since multiple corticosteroids exist, each with different potencies, half-lives, and mineralocorticoid activities, converting between them accurately is essential to ensure therapeutic consistency and minimize side effects.
Steroid conversion calculators standardize this process by applying established equivalence tables. For example, prednisone, hydrocortisone, dexamethasone, and methylprednisolone all have different potencies. Administering an incorrect equivalent dose may lead to under-treatment, resulting in persistent disease activity, or over-treatment, increasing risks such as hyperglycemia, hypertension, osteoporosis, adrenal suppression, and infection.
These calculators are particularly valuable in clinical scenarios such as tapering therapy, switching from oral to IV routes, or adjusting for drug availability. While they guide equivalent dosing, clinical judgment remains critical, as factors like patient response, comorbidities, and treatment duration influence outcomes.
Overview
When to use
Why use
Evidences
Interpretation
Steroid | Dosage | Action duration |
Hydrocortisone | 20 mg | Short acting |
Prednisone/Prednisolone | 5 mg | Intermediate |
Methylprednisolone | 4 mg | Intermediate |
Dexamethasone | 0.75 mg | Long acting |
Betamethasone | 0.6 mg | Long acting |
Equivalency framework (StatPearls – Glucocorticoid therapy): Common oral/parenteral anti-inflammatory equivalences center on prednisone 5mg ≈ prednisolone 5mg ≈ methylprednisolone 4mg ≈ triamcinolone 4mg ≈ hydrocortisone 20mg ≈ dexamethasone 0.75mg ≈ betamethasone 0.6mg; mineralocorticoid activity varies substantially (hydrocortisone and fludrocortisone highest; dexamethasone/betamethasone negligible).
https://www.ncbi.nlm.nih.gov/books/NBK596734/
Study focus and design: Classic comparative human study evaluating the relative potency and duration of action of systemic glucocorticoids namely hydrocortisone, prednisone and dexamethasone, by measuring suppression and recovery of the hypothalamic–pituitary–adrenal (HPA) axis after dosing
https://pubmed.ncbi.nlm.nih.gov/888843/
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