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Home/Diagnosis/ICD-10 Coding for Systemic Inflammatory Response Syndrome

ICD-10 Coding for Systemic Inflammatory Response Syndrome

R65.10
R65.11
R65.20

Complete ICD-10-CM coding and documentation guide for icd-10 coding for systemic inflammatory response syndrome includes clinical validation requirements, medical necessity guidelines, and coding policies.

Also Known as:
SIRS
systemic response syndrome
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Key Information: ICD-10 Coding for Systemic Inflammatory Response Syndrome

Essential facts and insights about ICD-10 Coding for Systemic Inflammatory Response Syndrome

Use ICD-10 code R65.10 for systemic inflammatory response syndrome (sirs) of non-infectious origin without acute organ dysfunction, ensuring proper documentation in clinical notes.

Primary ICD-10-CM Codes

Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction

Billable Code
R65.10
Billable

Diagnostic Criteria

  • • Temperature >38°C or <36°C
  • • Heart rate >90 beats/min
  • • Respiratory rate >20 breaths/min or PaCO2 <32 mmHg
  • • White blood cell count >12,000/mm³ or <4,000/mm³ or >10% immature (band) forms

Applicable To

  • • SIRS due to non-infectious causes without organ failure

Important Notes

  • • Ensure the underlying condition is documented and coded first.

Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction

Billable Code
R65.11
Billable

Diagnostic Criteria

  • • SIRS criteria plus evidence of organ dysfunction such as acute renal failure, respiratory failure, etc.

Applicable To

  • • SIRS due to non-infectious causes with organ failure

Important Notes

  • • Ensure organ dysfunction is documented and coded.

Severe sepsis without septic shock

Billable Code
R65.20
Billable

Diagnostic Criteria

  • • Sepsis criteria plus evidence of organ dysfunction without shock.

Applicable To

  • • Severe sepsis without shock

Important Notes

  • • Ensure organ dysfunction is documented and coded.

Severe sepsis with septic shock

Billable Code
R65.21
Billable

Diagnostic Criteria

  • • Sepsis criteria plus evidence of organ dysfunction and shock.

Applicable To

  • • Severe sepsis with shock

Important Notes

  • • Ensure shock is documented and coded.
Frequently Asked Questions

What is the ICD-10 code for SIRS?

The ICD-10 codes for SIRS include R65.10 for non-infectious origin without organ dysfunction and R65.11 with organ dysfunction. For severe sepsis, use R65.20 or R65.21.

How do you code SIRS due to pancreatitis?

For SIRS due to pancreatitis, code the underlying condition (e.g., K85.9) first, followed by R65.10 if no organ dysfunction is present.

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