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Home/Diagnosis/ICD-10 Coding for Mast Cell Activation Syndrome

ICD-10 Coding for Mast Cell Activation Syndrome

D89.41
D89.43

Complete ICD-10-CM coding and documentation guide for icd-10 coding for mast cell activation syndrome includes clinical validation requirements, medical necessity guidelines, and coding policies.

Also Known as:
MCAS
Mast Cell Activation Disorder
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Key Information: ICD-10 Coding for Mast Cell Activation Syndrome

Essential facts and insights about ICD-10 Coding for Mast Cell Activation Syndrome

Use ICD-10 code D89.41 for mast cell activation syndrome, unspecified, ensuring proper documentation in clinical notes.

Primary ICD-10-CM Codes

Mast cell activation syndrome, unspecified

Billable Code
D89.41
Billable

Diagnostic Criteria

  • • Serum tryptase level ≥ (1.2 × baseline) + 2 ng/mL
  • • Multi-organ involvement documented

Applicable To

  • • Idiopathic MCAS

Important Notes

  • • Ensure documentation supports the use of this code with specific lab results and symptom descriptions.

Secondary mast cell activation syndrome

Billable Code
D89.43
Billable

Diagnostic Criteria

  • • Documentation of underlying condition causing MCAS
  • • Tryptase elevation during episodes

Applicable To

  • • MCAS secondary to another condition

Important Notes

  • • Ensure the underlying condition is documented and coded first.
Ancillary Codes

Additional codes that may be used with this diagnosis

T78.2XXA

Use for acute anaphylactic episodes related to MCAS.

Anaphylaxis

R20.9

Document cutaneous symptoms associated with MCAS.

Cutaneous flushing

Frequently Asked Questions

What is the ICD-10 code for mast cell activation syndrome?

The ICD-10 code for mast cell activation syndrome is D89.41 for unspecified cases, with more specific codes like D89.43 for secondary conditions.

How is MCAS diagnosed?

MCAS is diagnosed through clinical criteria including elevated serum tryptase levels and multi-organ involvement during episodes.

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