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HomeICD-10 CodesI21
ICD-10-CM
Non-billable

I21

Classification
Category:Diseases of the circulatory system
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Coding Guidance
I21 should not be used for reimbursement purposes as there are more specific codes below it that contain a greater level of detail.
Inclusion Terms
  • cardiac infarction
  • coronary (artery) embolism
  • coronary (artery) occlusion
  • coronary (artery) rupture
  • coronary (artery) thrombosis
  • infarction of heart, myocardium, or ventricle
  • myocardial infarction specified as acute or with a stated duration of 4 weeks (28 days) or less from onset
Excludes 2
I25.2
old myocardial infarction
I24.1
postmyocardial infarction syndrome
I22
subsequent type 1 myocardial infarction
P04-P96
certain conditions originating in the perinatal period
A00-B99
certain infectious and parasitic diseases
O00-O9A
complications of pregnancy, childbirth and the puerperium
Q00-Q99
congenital malformations, deformations, and chromosomal abnormalities
E00-E88
endocrine, nutritional and metabolic diseases
S00-T88
injury, poisoning and certain other consequences of external causes
C00-D49
neoplasms
R00-R94
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
M30-M36
systemic connective tissue disorders
G45
transient cerebral ischemic attacks and related syndromes
Use Additional Code
/codes/Z77.22
exposure to environmental tobacco smoke
/codes/Z87.891
history of tobacco dependence
/codes/Z57.31
occupational exposure to environmental tobacco smoke
/codes/Z92.82
status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility
/codes/F17
tobacco dependence
/codes/Z72.0
tobacco use

More Specific Codes

I21.0
ST elevation (STEMI) myocardial infarction of anterior wall
I21.1
ST elevation (STEMI) myocardial infarction of inferior wall
I21.2
ST elevation (STEMI) myocardial infarction of other sites
I21.3
ST elevation (STEMI) myocardial infarction of unspecified site
I21.4
Non-ST elevation (NSTEMI) myocardial infarction
I21.9
Acute myocardial infarction, unspecified
I21.A
Other type of myocardial infarction
I21.B
Myocardial infarction with coronary microvascular dysfunction

External Resources

2025 ICD-10 guidelines from CMS.gov