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HomeICD-10 CodesC49
ICD-10-CM
Billable

C49

Classification
Category:
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Coding Guidance
Coding Guidance C49 should not be used for reimbursement purposes as there are more specific codes below it that contain a greater level of detail. See Related Codes to drill down to more specific billable codes for appropriate reimbursement.
Includes
From
  • malignant neoplasm of blood vessel
  • malignant neoplasm of bursa
  • malignant neoplasm of cartilage
  • malignant neoplasm of fascia
  • malignant neoplasm of fat
  • malignant neoplasm of ligament, except uterine
  • malignant neoplasm of lymphatic vessel
  • malignant neoplasm of muscle
  • malignant neoplasm of synovia
  • malignant neoplasm of tendon (sheath)
Excludes 1
From
  • malignant neoplasm of cartilage (of):
  • articular ( C40-C41 )
  • larynx ( C32.3 )
  • nose ( C30.0 )
  • malignant neoplasm of connective tissue of breast ( C50 .-)
Excludes 2
From
  • Kaposi's sarcoma of soft tissue ( C46.1 )
  • malignant neoplasm of heart ( C38.0 )
  • malignant neoplasm of peripheral nerves and autonomic nervous system ( C47 .-)
  • malignant neoplasm of peritoneum ( C48.2 )
  • malignant neoplasm of retroperitoneum ( C48.0 )
  • malignant neoplasm of uterine ligament ( C57.3 )
  • mesothelioma ( C45 .-)

More Specific Codes

C49.0
Malignant neoplasm of connective and soft tissue of head, face and neck C49.0
C49.1
Malignant neoplasm of connective and soft tissue of upper limb, including shoulder C49.1
C49.2
Malignant neoplasm of connective and soft tissue of lower limb, including hip C49.2
C49.3
Malignant neoplasm of connective and soft tissue of thorax C49.3
C49.4
Malignant neoplasm of connective and soft tissue of abdomen C49.4
C49.5
Malignant neoplasm of connective and soft tissue of pelvis C49.5
C49.6
Malignant neoplasm of connective and soft tissue of trunk, unspecified C49.6
C49.8
Malignant neoplasm of overlapping sites of connective and soft tissue C49.8
C49.9
Malignant neoplasm of connective and soft tissue, unspecified C49.9
C49.A
Gastrointestinal stromal tumor C49.A
C00-D49
C00-D49 - Neoplasms

External Resources

2025 ICD-10 guidelines from CMS.gov